Hello Health Champions today I want to talk about what you need to know before you start a weight
loss medication like ozempic and I've gotten tons and tons of questions hundreds literally
where people are wondering about these weight loss drugs because they seem to work so people
say things like I'm interested in knowing how this will affect my body I'm a type 2 diabetic
but I had a GI reaction someone says my doctor is pushing me to go on ozempic I'm refusing too
many serious side effects and the weight comes right back when this continued I don't want to
be a guinea pig and then Beavis and Butthead says there are two ways to lose weight one's
called wegovy and the other is called ozempic so these contain the active ingredient we're going
to talk about today nothing else works and we are all living proof thank God modern medicine finally
got something right so did Beavis and Butthead get this right we're going to talk talk about weight
loss medications that contain something called semaglutide and we're going to talk about the
results people are getting about the mechanism because that's critical to understand what it
does and what else it does and because when we understand the mechanism we can figure out if it's
a good idea typical results based on data they've gathered are that after one year 63 percent of
people have lost at least five percent of their body weight which means if you weighed 200 pounds
or 200 kilos whichever unit you can do the math you're down to 190 and 27 percent lost at least
10 percent meaning you gone from 200 to 180. so we would probably have to say that yes this works
there are some benefits in terms of weight loss and like we will talk about also diabetes and in
insulin resistance but does it work better than blank that's the question I think there are some
people who can be helped by this who have really stubborn weight where nothing else have worked but
does it work better than other things that we could do such as fasting and low carb because
it's very clear that a lot of people using this have never really seriously tried fasting or low
carb but then the question is can you do this for a while and then get off is this something
you do for three months or six months or a year and then you're done and your body has restored
its balance and you can just go on with life also does it keep working if you do take it long term
do the effects stay the same or does it kind of taper off but most importantly even if it works
are there some consequences the active component is called semaglutide and that's what we call a
glp-1 Agonist an Agonist works the same as an antagonist works the opposite and glp1 stands
for glucagon like peptide one that's a hormone that the body makes itself so this semaglutide
works the same it has the same effect as this glp1 Agonist and this is a hormone that the body
releases at the end of a meal so when we have eaten we've given the body some resources this
is one way that the body recognizes hey we are full we're satisfied so it signals that to the
body it signals fullness but it also signals that hey we got got a bunch of food let's release some
insulin so we can take care of this food so we can bring the blood sugar down and process it get it
into the cell and start some metabolic processes so both of these are excellent for controlling
type 2 diabetes because the insulin will bring down blood glucose but when we signal fullness
we end up eating less so even though it raises insulin it actually works for weight loss and
diabetes control but we really have to understand a few more things that it does it reduces the rate
and amount of gastric emptying so the food sits in the stomach for a long long time and this is part
of why we don't just get the signal of fullness but we feel full for a good bit longer and this
also has a lot to do with the side effects which we'll come back to it decreases gastric motility
so the stomach normally churns and mixes pretty much on going to mix the food with
the digestive juices and that's part of digestion of breaking down the food and extracting nutrients
and furthermore this glp-1 reduces the acid secretion so we're going to have less stomach
acid and we need to understand all these and we'll go through these in detail now these drugs have
been called blockbuster drugs because they're some of the most popular drugs around there's 60 000
prescriptions written every week for these even though they're very very expensive and the reason
is of course it works and it increases insulin it decreases blood glucose and it decreases appetite
so this means that you can lose weight with no responsibility or with much less responsibility
than you might otherwise have to and for a lot of people they continue to eat the standard American
diet lots of sugar lots of processed food and grain and tons of carbs and they still get results
so in other words you can have your cake and eat it too and what could be better than that so of
course it's very popular and I found a story some people had shared their experience and we're going
to call them the Smiths even though they were actually called something else in the article
they were very affluent they were successful but they rather pay attention to their careers than
their health they were in their 50s they had type 2 diabetes they were both overweight and
they said that because of ozempic they had changed their relationship to food they had lost 15 pounds
in several months time and the A1C had gotten very much under control from a pre-diabetic or diabetic
range to a normal range and the article quoted them saying things like I can eat half a sandwich
and be so full I need to stop I'll put the other half away for later they would say hey what's for
dinner and the answer would be I don't care let's just have a few bites of cereal and the husband
would say things like well I won't follow a diet I won't count carbs or watch the amount of sugar
I eat I just won't do those things so here's the thing I want to point out that they said they had
changed their relationship to food but in my mind they hadn't changed anything they it has taken a
chemical they had taken a medication that went in and interfered and simply blunted their response
to food they they flattened their desire but they hadn't learned anything they hadn't really
changed anything they still ate the same stuff now for some people they still have success doing
that for other people they have to take some other measures such as exercise and some dietary changes
on top of the medication so here's a key point this medication actually appears to help people
with weight and diabetic markers such as blood sugar and A1C and that's a great thing but blood
sugar and insulin resistance is not everything there is about health it's the majority of people
have that problem but because you reverse it doesn't mean you cover 100 of your health issues
we are a nation a planet at this point who is overfed and undernourished and if you
are nutrient deficient and you're eating 3 500 calories of depleted food of nutrient deficient
processed foods which we do in the U.S on average it's like 3 700 or something and then you take
a medication that suppresses your appetite and now you eat 2 000 calories of nutrient deficient
depleted food how is that going to make you healthier yes you're going to fix what your
insulin resistance gets a little better but are you getting healthier just because you wake fix
one problem doesn't mean it's all gone you solve one thing and you create several new ones and
if you fix the insulin resistance that might take care of you it might look much better in the next
several months to a few years but what happens after that what happens over a few decades so
let's look a little bit further on if this is a good idea and let's look at how normal physiology
operates so in your body you have something called the autonomic nervous system that's the
part of your brain and nervous system that handles everything behind the scenes for you it processes
billions of bits of information every second which is a million times more than your conscious mind
processes so there's a tons of information that is processed on your behalf everything is fine-tuned
and regulated and the autonomic nervous system supervises your endocrine system your hormones and
your hormones are part they they handle behavior and mood and so forth but also there are hormones
that affect your digestive system like glp1 that we're talking about and humans just like
every other animal on the planet have certain needs we need certain resources and therefore
because of the need our autonomic nervous system our hormones create a desire called
appetite and every animal on the planet go out to eat every day they try to find something it's not
because they don't have anything better to do it's because they need some resources and then once we
find something now we start eating and there's a whole slew of steps involved to get this process
completed we start chewing it to breaking it down into smaller pieces we release some saliva with
enzymes to start breaking it down then we have gastric juices like acid hydrochloric acid that
activate peptides that are enzymes that break down protein then like we said we have motility
first the stomach starts churning and mixing and then it starts moving through the digestive tract
and it completes the digestive process and the stomach will empty it will move things through
at a certain rate so it needs to be in the stomach for a certain amount of time and when the body is
done with that with the churning and the digestive juices then it moves it on out and now the rest
of the digestive system the small intestine the large intestine can finish the absorption of the
nutrients and we can turn all these resources into energy and tissue into new body parts and
I just want to emphasize that all of these steps have been in place in every mammal on the planet
for eons and there's nothing random about it every step has its purpose and it's there to complete
the process of getting resources into the body and assimilating them appropriately and now we go add
semaglutide which will decrease the response of the autonomic nervous system so the body still
needs the same amount of resource sources but we have no desire to go and acquire them we don't
care whether we get the resources or not we're just not going to get hungry then this medication
also reduces the gastric juices which means that now we have less acid and that acid acts as an
immune barrier if you ingest some bacteria they're basically supposed to die in that acid vat but if
we don't make the juices now we've lost at least part of that immune barrier we also cannot digest
proteins very well the proteins that are supposed to become the building blocks the tissues of the
body without the acid we're not activating the pepsin which starts breaking down protein we
reduce the motility the stomach doesn't move and churn it doesn't mix it just sits there so now
without that churning and mixing we are losing an important aspect of digestion and breaking
down that food and the semaglutide also reduces the stomach emptying so the food basically just
sits there for a long long time and this has a lot to do with the side effects that they're observing
and these are pretty substantial so it's not like one or two percent here and there that experience
these side effects about 20 percent of people will have nausea and depending on the dose if it's a
higher dose as much as 40 percent of people will get nauseous we also have vomiting nine percent
of people would vomit and we have diarrhea in eight percent of people so these numbers are are
pretty substantial but if you watch the headline lately there's been some much much more serious
side effects and that is called gastroparesis and there are lots of people who report gastroparesis
which is basically a paralysis of the stomach not only does it move slowly or move a little bit it
stops all together they put food in there and it just sits there and one lady reported that she
went to a restaurant she had one bite and started throwing up and they took her to the emergency
room and they checked out her stomach and the food from the previous day was still in the stomach
that can't be good and in other people they find that even years later after they have discontinued
these drugs some of these side effects still remain that they still have gastroparesis they
still have vomiting years and years later now no one really knows why some of these effects go on
for a long long time and why they might become even permanent but I want to share something
with you some a way that we want to think about these things and when want to question the things
that we're doing and it has to do with half-life so every hormone the body makes has a half-life
the body has a plan for this hormone it's only supposed to last so long and when we compare
the body's own the glp-1 to the man-made version of the glp-1 they're dramatically different the
bodies version has a half-life of two minutes that means after two minutes only half of the initial
release is there after four minutes 25 is left and so forth so after 10 minutes the effect is mostly
gone so the body is planning for this to only work a very very short time in terms of slowing
down the secretion of stomach acid and gastric emptying and appetite suppression and so forth
but when we compare that to the man-made version how many minutes would you think
that the half-life is of that well how about one week that's a lot of minutes so we have something
where the body intended it to last a very short time to basically gone in 10 minutes and now we
put something in that has a virtually permanent effect so the appetite suppression and the gastric
acid suppression and the slowing of the stomach now we have something that is always there and if
we have something that suppresses function ongoing that's obviously very very different than the plan
the body had in mind and then they're giving you some helpful hints for managing these side effects
of course so they say eat bland food eat low-fat foods that are low in fiber things like crackers
toast and white rice yeah that'll really solve the problem so eating things that have even less
nutrient even less resources how's that going to get you healthy so this medication comes with a
lot of side effects but here's what we also need to understand about side effects that when we use
that word in our standard language then it means an undesired effect that has resulted in a symptom
something that we notice something manifest but I want to try to give you another understanding of
side effect the way I look at it so my definition is that a side effect is any disruption of normal
physiology that if the body normally has its way of doing things we give it resources it uses those
resources it has a plan there's a mechanism for everything now anything foreign any medication any
chemical that we take that changes that balance is going to have a consequence or a side effect
fact whether we notice it or not now a lot of people probably think that I am an anti-medication
which I'm not I'm only against most of it or rather the way most of it is being used
so I'm all for using medication for emergencies where they can save life where there is a crisis
where something has gone out of control they can save lives but we have to understand that
most health problems are lifestyle problems it's things that we have created ourselves knowingly
or unknowingly and the only way to deal with a lifestyle problem is to make a lifestyle change
so a few more things about this semaglutide that they say that rebound is common or even
expected so basically what that means is that over time there is a lessening effect the body
tries to defend itself against this chemical so the appetite suppression might not be the
same all the time and also more importantly if you stop this medication then you will start
gaining weight again it will the body will bounce right back unless you have made such powerful
changes in your lifestyle that you control it with food and exercise and you eat real food
so basically this is a lifetime medication once you get on it expect it to go on forever pretty
much also a lot of people will still need to make Lifestyle Changes like we talked about before some
people can be lazy and keep eating garbage and get some results but for a lot of people with stubborn
weight then they will still need to make lifestyle changes some other issues that they mention is
that a lot of times this is covered by insurance and it's very expensive so Insurance may not be
interested in covering this year after year after year especially not without raising premiums and
if you pay this out of pocket some of the numbers that I saw was like a thousand dollars a month and
it sometimes baffles me how incredibly intelligent the human species is and yet we are clever enough
to be really really stupid that that we have completely parted ways with nature we're the only
species who have separated ourselves completely from nature to create artificial environments
and artificial foods and in doing that we are basically creating all disease the vast majority
of the disease that we're suffering from today we have created and then we develop so-called
Health Care Systems which are really sick care and symptom treatment systems and we spend not a
little bit of money but virtually all the money we have left trillions and trillions of dollars and
what are we doing we're covering up and treating symptoms we're not addressing root causes we
create disease and then we spend trillions in just treating the effects of that and when we treat
symptoms instead of root causes of addressing root causes we're allowing the problem to continue
and we actually make it worse but we all have different perspectives and what I'm sharing here
is just my perspective I'm not pointing fingers or saying that anyone's doing anything wrong you
always have your choice and you can either eat crap and take medications and then from age 40
or 50 or so then like a lot of people you might develop fatigue and brain fog you might get some
chronic pain maybe start developing poor sleep you might have some reduced mobility and like a
lot of people you start developing type 2 diabetes cardiovascular disease and no neuropathy so the
majority of population will experience a reduced quality of life and be on multiple medications
from age 40 or 50. this is your choice there's nothing wrong with that if that model works for
use that's all the best that you want then go for it but you do have another choice and that
is to be a health Champion that's what I'm always talking about on this channel and that means that
you address the root cause you understand that this body is only adapting to insult that we're
doing things through our lifestyle that the world has changed more in 50 years than the previous 50
000 and if we understand what that impact is on the body now we can start addressing root
causes we can start honoring and supporting our bodies and our physiology and start eating real
food which in my opinion my experience is low carb high fat and it doesn't mean everyone needs to be
keto it doesn't mean everyone needs to be extreme low carb but it means fat is really healthy if we
eat good fat and most people are eating way way way too much carbohydrate and nobody should have
their diet based on carbohydrates and grains and we have to eat food that has nutrients that
provide the resources and in doing that we're going to create a balance and Natural Balance
between hunger and satiety we have this delicate infinite intelligence that can regulate these
things if we give the body the right resources and the next most important thing is to move the body
on a regular basis your body is made for movement it's what drives every physiological process it
drives the nervous system you cannot have optimal health without regular movement and by doing all
of this for a period of time at the same time now you can start living to your potential which
is going to be different for different people we have been blessed to different degrees with
genetic blueprint but you do this first and then you start looking elsewhere if you still need help
controlling some symptoms if you enjoyed this video you're going to love that one and if you
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